Foreword

The tumor organoid-immune co-culture model is an in vitro experimental system integrating tumor organoids with immune cells, capable of simulating the interactions between tumor cells and the immune system within the in vivo tumor microenvironment. It holds significant value in basic research, translational medicine, and clinical applications. Typically, this model involves co-culturing organoids and immune cells that have been separately cultured in vitro. The growth status of tumor organoids during in vitro culture, the maintenance of immune cell activity and function, and the faithful reproduction of the respective functions of tumor organoids and immune cells within the co-culture system are critical factors determining the reliability of model results and the predictive efficacy of preclinical studies.

bioGenous offers a comprehensive solution for tumor organoid-immune cell co-culture, breaking down technical barriers to simplify complex experiments and accelerate research translation!

Make every tumor organoid culture a milestone in cancer research.

Launch your tumor immunology research 2.0 today—because only more realistic models can yield life-saving answers!

1. Tumor Organoid Culture Full Process Kit

A standardized reagent system covering the entire organoid life cycle, comprising six core components:

• Primary Tissue Storage Solution—Maintains viability and functional integrity of ex vivo tissue cells
• Base Medium — Biomimetic matrix medium
• Tissue Digestion Solution — Efficient cell suspension preparation
• Organoid Basal Medium— Supports long-term stable proliferation
• Organoid Digestion Solution — Gentle dissociation with minimal damage
• Organoid Cryopreservation Medium — Ensures high recovery activity

2. T-Cell Expansion Medium

A specially formulated cell culture medium designed to support T-cell expansion in peripheral blood mononuclear cells (PBMCs), also suitable for reactivation and expansion of T cells.

3. OrganoidpleX Basal Medium

Integrate essential components of the basal medium required for in vitro proliferation of tumor organoids with cytokines necessary for maintaining immune cell functional homeostasis, thereby creating a biomimetic co-culture microenvironment that simulates the tumor-immune cell interaction interface.

Technical Services

We provide a co-culture technology system based on tumor organoids and immune cells, offering a comprehensive solution covering the entire chain from immune cell activation, tumor organoid construction, co-culture system optimization, to model efficacy validation. By creating organoid models that simulate the tumor immune microenvironment, we conduct in-depth analysis of immune evasion mechanisms and immunotherapy responses. This supports the development of drug combination strategies and personalized efficacy prediction, delivering highly biomimetic, customizable, innovative solutions for tumor immunotherapy research and development.

Service Process

Service Content and Schedule

Service Cases