Foreword

Traditional brain organoid research heavily relies on induced pluripotent stem cell (iPSC) technology. While capable of simulating certain neurodevelopmental processes, it suffers from significant drawbacks, including lengthy cycles (exceeding 3 months), low functional maturity, and pronounced batch-to-batch variability. These limitations severely constrain drug screening and the reliability of disease models. BioGenous™ once again leads innovation by introducing its serum-free human and mouse brain organoid culture kits! Derived from human and mouse brain tissue and utilizing a serum-free, end-to-end system, this breakthrough overcomes the limitations of iPSC technology. It enables the efficient construction of highly biomimetic, functionally complete brain organoids, establishing a new paradigm for neuroscience research and propelling brain science studies to a new level.

Product Highlights

Standardized Scalable Brain Organoid Cultivation

• Innovation at the Source, Efficient Expansion

Cycle Shortened by 85%: Organoid passage and expansion cycles take only 12-14 days, significantly faster than the average 3+ months for traditional iPSC induction cycles.

High-Efficiency Expansion, Long-Term Stability: Supports long-term stable expansion with >90% viability, overcoming the challenge of sustaining iPSC organoids over extended periods.

• Highly Functional Mimicry, Precisely Simulating Brain Development and Disease

Naturally Preserves Spatiotemporal Characteristics: Directly reproduces cortical layering without complex induction.

More Authentic Pathological Models: Accurately simulates neurodegenerative diseases and brain tumor development.

• Serum-Free Workflow, Balancing Safety and Stability

Defined Components: Serum-free with clearly identified ingredients.

Safety and Stability: Manufactured and managed under GMP standards with minimal batch-to-batch variation.

Product Data

• Mouse Fetal Brain（Expansion) Organoid Kit

P1-D2                 P1-D8

P3-D4             P3-D8

Figure 1 E13.5 Bright-field images of first- and third-generation mouse brain organoids constructed from mouse embryonic brain tissue. Experimental materials require strict ethical review. (Scale bar, 200 μm)

• Mouse Fetal Brain (Differentiation) Organoid Kit

Product Information