The bioGenous™ Smart StarMap Microscope integrates three advanced imaging modes—highly sensitive multi-color fluorescence imaging, phase contrast, and bright field imaging—combined with high-speed automatic shooting and precise tracking systems. Its optimized optical path and high-resolution CMOS camera are specifically designed for organoid tracking. The microscope offers various imaging modes to meet diverse experimental needs, while the high-throughput automatic shooting system enhances efficiency, saving over 80% of imaging time for researchers.
This integrated organoid localization imaging system delivers several key advantages: clear organoid imaging, accurate tracking and positioning, and robust automated programmed imaging. It is compatible with various sample types, including all well plates, cell culture dishes, and tissue sections from different brands, offering a comprehensive and efficient solution for high-throughput organoid imaging experiments.
The system supports continuous growth monitoring of organoids, staining and identification of tumor organoids, and full-field imaging across multi-well plates and multiple focal planes, making it highly suitable for high-throughput drug susceptibility testing.

Core Adavantages

1)Strong adaptability: The system features three observation modes—phase contrast, bright field, and fluorescence—allowing it to accommodate a wide range of samples, including 6-well to 384-well cell culture plates, petri dishes, and tissue sections from various brand

2)Clear imaging: Equipped with an infinite flat-field achromatic optical system, for a variety of culture plates, it can achieve high noise ratio, high resolution and high contrast imaging effect of organoids.

3)Multi-color fluorescence:Multiple fluorescence channels are selected to collect fluorescence images of organoids, and high-definition fluorescence image sensors are equipped to realize multi-dimensional imaging and analysis of bright field and fluorescence.

4)Continuous fixed-point tracking: Through X-Y-Z three-axis fixed-point tracking, the system can record the coordinates of organoids at different positions across various wells in real-time. This allows for continuous monitoring and tracking of the dynamic changes in organoids, as well as alterations in cell structure, morphology, and function

Growth monitoring of mouse small intestinal organoids

Double-click“hole position/coordinate point” for fast and automatic tracking and positioning

5)Automatic multi-focal plane full-hole scanning:It allows for the setting of various automated well plate scanning and Z-axis scanning programs, with the capability to stitch images for full-well field-of-view capture. Additionally, it can achieve rapid multi-focal plane imaging of organoids across the entire well plate.

Z-axis superposition of human tracheal organoids

Automatic Z-axis scanning of human tracheal organoids (10 layers)