Smart Tissue Dissociation System SmartOrgan^TM Dissociator 

The bioGenous™ Smart Tissue Dissociation System, developed independently by bioGenous™, is engineered to rapidly dissociate primary tissues into single cells or cell clusters. The system includes the SmartOrgan™ Dissociator device and specialized tissue dissociation reagents. By tailoring the dissociation reagents and programs to different tissue types, this system offers enhanced efficiency, high cell viability, intelligent operation, and uniformity. Compared to traditional enzymatic dissociation methods, the Intelligent Tissue Dissociation System significantly accelerates tissue dissociation while producing high-viability, high-quality cell suspensions. The resulting dissociated cell clusters are uniformly sized, making them ideal for downstream applications such as organoid culture, flow cytometry analysis and sorting, and single-cell sequencing.

Advantages

• 1. Multi-Channel Dissociation: The bioGenous™ Smart Tissue Dissociation System is equipped with a thirteen-channel dissociation module, offering the flexibility to select different dissociation channels based on the size and type of tissue. This multi-channel capability allows for customized dissociation protocols, ensuring optimal results for various tissue types.

• 2. Automation: The bioGenous™ Smart Tissue Dissociation System includes multiple preset dissociation programs, enabling users to select customized protocols that are tailored to the specific characteristics of the tissue sample. This feature ensures optimal dissociation outcomes by allowing precise control over the process, enhancing both the efficiency and quality of the final cell suspension

• 3. Intelligent and Flexible: The system allows real-time monitoring of operational status, enabling users to retrieve samples at any time and adjust or optimize the dissociation process as needed.

• 4. High Viability and Uniformity: By optimizing the dissociation conditions and processes, the system maintains high viability and uniformity of the tissue samples. The primary sample quality is excellent, with cell viability reaching up to 90%.

Figure 1. Post-dissociation of primary tissue samples, perform Trypan Blue staining. Scale bar: 100 µm.;

【bioGenousSmartOrgan^TM Dissociator VS Dissociation of traditional tissues】