Technical Services

Main Page > Technical Services
High-Throughput Drug Screening Based on Patient-Derived Organoid Libraries for New Drug Development
High-throughput drug screening mediated by an organoid library can address the issues of lacking suitable models and having a long development cycle in the process of biopharmaceutical innovation drug research and development.
Service Process

Service Content and Description

Fields:

Applicable to High-Throughput New Drug R&D of Patient-Derived Organoid Libraries

Keypoints:

High-throughput organoid modeling, quality control, identification, high content confocal imaging and analysis system, drug efficiency screening, validation, etc.

Service Process:

Screening of 100+ drugs using 3 patient-derived organoids, screening of 6-8 effective tumor growth inhibition candidates, and then validation of these drug candidates using 14 other patient-derived organoids.

Advancements:

1) High-throughput organoid culture and compatibility with high-throughput automated testing equipment;

2) Standardized platforms and methods to improve the reproducibility and stability of results;

3) Organoid drug screening technology reaches the level of leading international laboratories


Case Studies

Cell Stem Cell, in revision

Suitable Scenarios

Applicable to clinical oncology research, antitumor drug development workers, non-clinical preclinical new drug evaluation, small molecule drugs, tumor immunotherapy drug efficacy screening, etc.

 

Related Keywords:

CAR-T immunotherapy, tumor microenvironment, oncolytic virus, antibody drug, targeted drug, small molecule drug

分享到微信