Technical Services
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Human-Derived Organoid Pathogen Infection Models
This enables the rapid establishment of a human tissue-derived organoid pathogen infection model within 1-2 weeks, along with the design of pathogen-host infection experimental protocols. Comprehensive reagent services make it possible to conduct research validation and drug development projects for newly emerging and sudden viral infections, which were previously difficult to undertake due to ethical concerns or the lack of suitable models.
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Tumor Initiation Models
Tumor initiation models are established through human tissue-derived organoid models, using specific gene manipulation techniques to form tumor organoids with characteristics consistent with those of tumors. This allows for real-time observation of the progression of tumor development and addresses the challenges in tumor drug development that arise due to ethical concerns and the lack of suitable models.
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PDOX Construction (Nude Mice, NSG, etc., Immunodeficient Mice)
Transplanting organoids with tissue-specific characteristics into immunodeficient mice such as nude mice or NSG mice enables dynamic simulation of tumor development and embryonic development processes, as well as high-throughput drug screening. The mouse transplantation also achieves in vivo validation.
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Organoid Genetic Manipulation Strategies
Organoid genetic manipulation can utilize the dynamic simulation, high-throughput nature, and short cycle times of organoid models to flexibly perform genetic manipulations, thus enabling the study of gene functions under specific conditions.
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