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C152121

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Product Introduction Technical Specifications Associated Products

Product Introduction

DESCRIPTION

Background	SB202190 is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 has anti-cancer activity and rescued memory deficits^[1][2]. SB202190 induces autophagy^[3].
M. W t	331.34
Formula	C₂₀H₁₄FN₃O
CAS No	152121-30-7
Storage	Powder	- 20°C	3 years
		4°C	2 year C₂₀H₁₄FN₃O
	In solvent	-80°C	6 months
		-20°C	1 month
Solubility	DMSO	100 mg/mL(301.80 mM; Need ultrasonic)
	Ethanol	12 mg/mL(36.22 mM)
	H2O	< 0.1 mg/mL(insoluble)

Technical Specifications

SB202190 (FHPI)_00.jpg

Associated Products