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中国（江苏）自由贸易试验区苏州片区苏州工业园区新平街388号22幢8层01-02&09-12单元

C152121

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DESCRIPTION

Background	SB202190 is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 has anti-cancer activity and rescued memory deficits^[1][2]. SB202190 induces autophagy^[3].
M. W t	331.34
Formula	C₂₀H₁₄FN₃O
CAS No	152121-30-7
Storage	Powder	- 20°C	3 years
		4°C	2 year C₂₀H₁₄FN₃O
	In solvent	-80°C	6 months
		-20°C	1 month
Solubility	DMSO	100 mg/mL(301.80 mM; Need ultrasonic)
	Ethanol	12 mg/mL(36.22 mM)
	H2O	< 0.1 mg/mL(insoluble)

技术参数

SB202190 (FHPI)_00.jpg